Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long Covid

Donate Now
Donate Crypto
Sign Up

Characterizing B cells in ME/CFS

STUDY AIM
This study aims to broadly evaluate B cell subsets, metabolism, viability, receptors, and antibodies in people with ME/CFS.
LEAD INVESTIGATORS
  • Christopher Armstrong, PhD
  • Paul Gooley, PhD
  • Jo Cambridge, PhD
  • Ben Wendel, PhD
UPDATES AND POTENTIAL

B cells secrete antibodies and are a major part of the adaptive immune system. Anomalies in B cell metabolism, CD markers and antibodies have been observed in ME/CFS. This may be due to something inherently disruptive within the B cells themselves.

Preliminary studies using immunoadsorption and/or plasmapheresis to remove the antibodies show positive effects in at least a subpopulation of ME/CFS patients.

STUDY HYPOTHESIS AND DESCRIPTION

A number of anomalies in B cells have been observed in the few studies conducted on ME/CFS patients. We want to expand this area of research to better understand these changes and determine if there are any potential anomalies in antibody production or metabolism that could be driving altered immune response.

STUDY DESIGN

There are several studies involved in this multi-site collaborative effort:

  • Monitoring metabolism and CD marker changes in fresh ME/CFS B cells compared to healthy B cells during proliferative (via activation) and non-proliferative periods.
  • Monitoring metabolism changes in immortalized B cells from ME/CFS and healthy controls during proliferation.
  • Observing B cell subsets and antibodies in bone marrow from ME/CFS patients compared to healthy and disease controls.
Facebook Twitter Youtube Instagram

Open Medicine Foundation Australia Limited is registered as a charity with the Australian Charities and Not-for-profits Commission (ACNC). We are authorised by the Australian Tax Office as a deductible gift recipient (DGR). Donations of $2 or more are tax-deductible.

ABN 81 635 273 415

Open Medicine Foundation Australia Limited
C/O Accru Melbourne Pty Ltd
50 Camberwell Road
Hawthorn East VIC 3124

PRIVACY POLICY  | COOKIE POLICY| MEDICAL & OTHER DISCLAIMERS

CONTACT US

Copyright © 2023 Open Medicine Foundation. All Rights Reserved.

OMF Australia accepts donations of Cryptocurrencies

Make the most of your donation by donating your Bitcoin, Ethereum, and other cryptocurrencies directly to OMF Australia rather than selling and donating the after-tax proceeds.

  • Your tax deduction will be equal to the fair market value of the donated cryptocurrency (as determined by a qualified appraisal).
  • Donors should consult with a tax advisor for properly recording this donation on a personal tax return.


OMF Australia can accept cryptocurrency donations of any amount. 

Donating cryptocurrency is a non-taxable event, meaning you do not owe capital gains tax on the appreciated amount and can deduct it on your taxes. This makes Bitcoin and other cryptocurrency donations one of the most tax-efficient ways to support your favorite cause. If you want to learn more about how donating crypto can lower your taxes, check out thegivingblock.com/faq.

Talk to a crypto-savvy tax professional or connect with The Giving Block to get connected with one.

We accept the following cryptocurrencies: Bitcoin (BTC), Ether (ETH), Litecoin (LTC), Bitcoin Cash (BCH), Zcash (ZEC), Gemini Dollar (GUSD), Basic Attention Token (BAT), Chainlink (LINK), 0x (ZRX), Storj (STORJ), Dai (DAI), Amp (AMP), The Graph (GRT), UMA (UMA), 1inch (1INCH).

ATO Crypto asset investment & tax