Post-viral Encephalopathy
Herpes Simplex Encephalopathyand the Development of ME / CFS STUDY AIM The purpose of this study is to better understand what may cause the onset of ME/CFS after an initial infection. LEAD INVESTIGATORS Jonas Bergquist, MD, PhD Wenzhong Xiao, PhD Chris Armstrong, PhD Gabriel Westman, MD, PhD UPDATES AND POTENTIAL Based on data analysis, the team has […]
Studying ME/CFS Pathogenesis via Cerebrospinal Fluid
The goal of this research is to reveal more information about the role of immunology and neuroinflammation in ME/CFS, and the underlying mechanisms of related pathogenesis that takes place.
Multi-Omic Approaches to Solve Post-Acute COVID-19 (MOSAIC)
The purpose of this study is to facilitate early detection of ME/CFS in people with Long COVID and better understand disease progression.
Blood flow, neuroinflammation, and metabolism in ME/CFS (MELOPIS)
The study aims to explore the structural, neuro-vascular, and biochemical differences in the brains of individuals with ME/CFS, Long COVID, and POTS to elucidate the underlying pathology and identify potential targets for effective treatment strategies.
Personalised Treatment Trials (TOTEM)
The study aims to deeply characterise patients before, during and after treatments are trialled through their GP. Producing large scale data in combination with treatment outcome will be used to produce a predictive algorithm to improve the connection of patients to appropriate treatment options sooner.
Tracking Hormone Fluctuations in ME/CFS (MELLOW)
The study aims to investigate how hormone fluctuations in individuals with ME/CFS and Long COVID, compared to healthy controls, impact metabolism and immune pathways by measuring hormones, metabolites, and inflammation markers in biofluid samples.
Vascular Study of Orthostatic Intolerance in ME/CFS
The study aims to investigate the effects of supine vs upright exercise on cerebral blood flow, blood pressure, heart rate, and the presence of autoimmune antibodies in ME/CFS patients with orthostatic intolerance, compared to controls, to understand the underlying mechanisms and differences in symptom severity and post-exertional malaise.
Crash-Course: Studying PEM in ME/CFS, PTLDS, Long COVID
The study aims to compare biological markers during mild symptoms and flare/PEM events in individuals with ME/CFS, alongside PTLDS and Long COVID patients, using finger-prick blood samples and continuous data from wearable sensors to understand symptom variability.
AusME Biobank Biomarker Project
The study aims to utilise the Australian ME/CFS biobank for metabolomics analyses and other assays to identify potential biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, contributing to a comprehensive dataset for large-scale analysis.
Temporally Resolved Omics Tracking of ME/CFS (TROT-ME)
Temporally Resolved Omics Tracking of ME/CFS (TROT-ME) Study AIM This study seeks to understand the biological mechanisms driving the symptomatology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using metabolomic and lipidomic high-throughput analysis and high-frequency blood sampling over a 6.5 to 7.5 hour period conducted at two separate sites (Melbourne and Uppsala). LEAD INVESTIGATORS Martin Lewis, […]