Big Win: Dr Chris Armstrong Appointed to NHMRC ME/CFS Guideline Committee
We’re proud to share some exciting news: Dr Chris Armstrong, Director of the OMF Melbourne ME/CFS Collaboration, has been appointed to the National Health and Medical Research Council’s (NHMRC) Clinical Guideline Development Committee for ME/CFS. Listening to the ME/CFS Community This significant appointment follows the Roundtable held in March 2024 at Parliament House in Canberra, […]
An Update from Dr Chris Armstrong: The Science Behind Hope
As we approach the end of the financial year, we’re sharing an update on important developments in ME/CFS research — work that is steadily improving our understanding of the biology behind this complex and often life-altering condition. Whether a person’s ME/CFS began decades ago or more recently after COVID-19 or another infection, the challenges are […]
Research Update: Refining a Diagnostic Model and Designing a New PEM Project
Today, we are excited to share an interview with Chris Armstrong, PhD, and post-doctoral researcher, Kathy Huang, PhD, about their ongoing ME/CFS research. Please consider making a donation today to support our ongoing research efforts and bring us closer to finding effective diagnostics and treatments for millions worldwide. Every contribution, big or small, makes a significant impact! Donate […]
OMF Australia Marks 4th Anniversary: Progress, Hope, and Our Path Forward
We recently marked a significant milestone – the fourth anniversary of Open Medicine Foundation (OMF) Australia – with a special gathering in Melbourne. Hosted at the historic Cranlana House, the event brought together the brilliant minds behind our research, board members, and key partners. It was a particularly meaningful occasion as we welcomed OMF Founder […]
New Publication: Harnessing AI and Big Data for Precision Medicine in ME/CFS and Long COVID

Big Data and Artificial Intelligence (AI) have great potential to advance precision medicine for ME/CFS and Long COVID. Dr. Chris Armstrong and his colleagues have recently published a paper titled “Machine learning and multi-omics in precision medicine for ME/CFS”. In this review, the team explores how machine learning and multi-omics (genomics, transcriptomics, proteomics, and metabolomics) […]
New Protocol Paper: Investigating ME/CFS Impact and Biological Mechanisms in Adolescents

The underlying biological mechanisms for ME/CFS remain unclear and have rarely been investigated in the adolescent population, despite this period representing an age peak in the overall incidence. We’re pleased to share the ‘Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME)’ protocol paper from the Melbourne ME/CFS Collaboration. From the Desk of Dr. Chris ArmstrongMelbourne […]
Announcement!!! A New Large-Scale ME/CFS Biomarker Study (BioQuest)!

We are excited to announce that, thanks to two very generous grants, we have successfully secured $800,000—one-third of our goal—that will allow us to initiate a large-scale ME/CFS biomarker study (BioQuest)! The Heart of the Matter OMF has received funding to start an ME/CFS biomarker study, called BioQuest. The goal of BioQuest is to identify […]
Groundbreaking Nature Publication: Dr. Armstrong’s Metabolomics Study Advances ME/CFS Diagnosis
Today, we are excited to share a new publication by Christopher Armstrong, PhD, & colleagues: “Discriminating ME/CFS and Comorbid Conditions Using NMR Metabolomics in UK Biobank.” The Heart of the Matter The OMF Melbourne ME/CFS Collaboration recently published an article on their project using metabolomics to identify ME/CFS. The team analysed metabolomics data on over […]
Video Update: Linking Brain Blood Flow, Neuroinflammation, Metabolism, and Hormones in ME/CFS, POTS, and Long COVID

Linking Brain Blood Flow, Neuroinflammation, Metabolism, and Hormones in ME/CFS, POTS, and Long COVID Watch Now The Heart of the Matter Neuroinflammation, altered cerebral blood, and dysregulated hormones have all been separately observed in ME/CFS in prior research. Dr. Armstrong and his team at OMF’s Melbourne ME/CFS Collaboration have designed a study to examine the […]
Life Improvement Trial (LIFT) has officially begun!
The Life Improvement Trial (LIFT) has officially begun! Conducting a proper clinical trial and ensuring all logistics are set up takes time, so we are excited to share that Open Medicine Foundation’s Life Improvement Trial (LIFT) has officially launched. Recruitment and screening began in August and the first participants have now been enrolled. What is […]