New Publication: Harnessing AI and Big Data for Precision Medicine in ME/CFS and Long COVID
Big Data and Artificial Intelligence (AI) have great potential to advance precision medicine for ME/CFS and Long COVID. Dr. Chris Armstrong and his colleagues have recently published a paper titled “Machine learning and multi-omics in precision medicine for ME/CFS”. In this review, the team explores how machine learning and multi-omics (genomics, transcriptomics, proteomics, and metabolomics) […]
New Protocol Paper: Investigating ME/CFS Impact and Biological Mechanisms in Adolescents
The underlying biological mechanisms for ME/CFS remain unclear and have rarely been investigated in the adolescent population, despite this period representing an age peak in the overall incidence. We’re pleased to share the ‘Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME)’ protocol paper from the Melbourne ME/CFS Collaboration. From the Desk of Dr. Chris ArmstrongMelbourne […]
Announcement!!! A New Large-Scale ME/CFS Biomarker Study (BioQuest)!
We are excited to announce that, thanks to two very generous grants, we have successfully secured $800,000—one-third of our goal—that will allow us to initiate a large-scale ME/CFS biomarker study (BioQuest)! The Heart of the Matter OMF has received funding to start an ME/CFS biomarker study, called BioQuest. The goal of BioQuest is to identify […]
Groundbreaking Nature Publication: Dr. Armstrong’s Metabolomics Study Advances ME/CFS Diagnosis
Today, we are excited to share a new publication by Christopher Armstrong, PhD, & colleagues: “Discriminating ME/CFS and Comorbid Conditions Using NMR Metabolomics in UK Biobank.” The Heart of the Matter The OMF Melbourne ME/CFS Collaboration recently published an article on their project using metabolomics to identify ME/CFS. The team analysed metabolomics data on over […]
Video Update: Linking Brain Blood Flow, Neuroinflammation, Metabolism, and Hormones in ME/CFS, POTS, and Long COVID
Linking Brain Blood Flow, Neuroinflammation, Metabolism, and Hormones in ME/CFS, POTS, and Long COVID Watch Now The Heart of the Matter Neuroinflammation, altered cerebral blood, and dysregulated hormones have all been separately observed in ME/CFS in prior research. Dr. Armstrong and his team at OMF’s Melbourne ME/CFS Collaboration have designed a study to examine the […]
Life Improvement Trial (LIFT) has officially begun!
The Life Improvement Trial (LIFT) has officially begun! Conducting a proper clinical trial and ensuring all logistics are set up takes time, so we are excited to share that Open Medicine Foundation’s Life Improvement Trial (LIFT) has officially launched. Recruitment and screening began in August and the first participants have now been enrolled. What is […]
Major Milestone: Australian Government Funds Update of ME/CFS & Long COVID Clinical Guidelines
We are thrilled to announce that, as a direct outcome of the Canberra Roundtable convened in late March and led by Emerge Australia with the support of Open Medicine Foundation Australia, the Australian government has committed funding to update the clinical guidelines for ME/CFS and Long COVID. The current clinical guidelines for ME/CFS are over […]
Video Update: Personalised Treatment Trials
The Heart of the Matter General practitioners (GPs) often trial different treatments with their ME/CFS and Long COVID patients. In partnership with GPs, by studying the outcomes of each treatment, the patient’s lived experience, and the personal history of the patient, the Personalised Treatment Trials project is looking to understand why someone may or may […]
Video Update: Food and Saline Infusions in ME/CFS Research
The Heart of the Matter Food and saline infusions are both known to have an impact on ME/CFS symptoms. The Melbourne ME/CFS Collaboration is aiming to identify responses to different foods using objective measures, which may also prove useful in future trials. The team will also try to understand the impact of saline infusions to […]
Video Update: MELLOW Study Explores Hormonal Fluctuations in ME/CFS and Long COVID
The Heart of the Matter Hormones impact the immune system and energy metabolism, which are both considered major parts of the biological cause of ME/CFS. Changes in hormone levels may impact the development of the disease and its severity. The MELLOW project aims to measure fluctuations in hormones across the menstrual cycle, and identify how […]
