We’re excited to share an interview with all of OMF’s Directors. This panel discussion focuses on the big picture and draws connections across OMF’s research portfolio.
An Interview with OMF’s Directors
Click here to read the video transcript.
The Heart of the Matter
- In an interview with Dr. Danielle Meadows, all of OMF’s Directors talk about how their overarching hypotheses of ME/CFS might explain how symptoms look different in different people.
- They also talk about how their research complements and connects to each other, including in areas like post-exertional malaise and what treatment strategies might look like in the future based on our findings so far.
- In addition to the discussion, Dr. Meadows shares a visual representation of how their hypotheses and research connect.
Dr. Danielle Meadows, OMF’s VP of Research Programs and Operations, conducted an interview with all of OMF’s Directors: Dr. Ronald Davis at Stanford Univ, Dr. Jonas Bergquist at Uppsala Univ, Dr. Wenzhong Xiao leading the computation team at Harvard and Stanford Univ, Dr. David Systrom at Harvard Univ, Dr. Alain Moreau at Univ of Montreal, and Dr. Christopher Armstrong at Univ of Melbourne. This panel discussion focuses on the big picture and drawing connections between the research within OMF’s portfolio.
OMF’s Directors each talk about how their overarching hypotheses of the disease explains the variability in symptom presentation. In addition, they discuss research findings from different projects that complement or validate each other, including the underlying mechanism of post-exertional malaise, styles of treatment strategies, and more.
On top of discussing the connections between their research, Dr. Meadows shares a visual representation of some of those connections. The graphic is provided below and shows how a failure to recover from triggers and risk factors (top left) leads to a complex web of dysregulated systems, and the interactions between these systems yield the disease phenotype that can vary from person to person.
