As we approach the end of the financial year, we’re sharing an update on important developments in ME/CFS research — work that is steadily improving our understanding of the biology behind this complex and often life-altering condition.
Whether a person’s ME/CFS began decades ago or more recently after COVID-19 or another infection, the challenges are real and often devastating. Our research is focused on uncovering the underlying mechanisms that may be shared across these different pathways, with the goal of informing diagnosis, care, and ultimately, treatment.
The Science Behind Hope
In the video below, Dr Chris Armstrong, Director of the Melbourne ME/CFS Collaboration, presents a detailed overview of a key area of investigation: how people with ME/CFS may rely more heavily on amino acids to produce energy, especially when the usual energy sources like fats and sugars aren’t being used efficiently.
This hypothesis builds on years of metabolomic research and is helping to shape a clearer picture of the metabolic dysfunctions involved in ME/CFS. While the theory is still being refined, it offers a valuable framework — beyond what is discussed in the video — to explore both symptoms and potential intervention points, including possible treatment targets, across diverse patient experiences.
Your Support Matters
This research is moving forward — but continued progress depends on support from people like you. Your end-of-financial-year donation will help us:
- Advance laboratory investigations into the root biology of ME/CFS
- Publish peer-reviewed findings that shape global research directions
- Develop evidence-based models to guide future treatments
- Support ongoing collaboration with leading scientists worldwide.
Every donation helps sustain this work — and brings us closer to answers for the estimated 1 in 30 people living with ME/CFS and related conditions.
Your contribution before 30 June will help sustain momentum — turning lab discoveries into meaningful improvements in quality of life.
Together, we’re not just funding research — we’re helping to change what’s possible for everyone living with ME/CFS.
