Search
Close this search box.

25-Day Metabolite Monitoring Study of ME/CFS patients

The study will meticulously analyse daily changes in metabolites from blood samples of individuals with ME/CFS over 25 days, to uncover the complex biological processes contributing to the condition and facilitate patient clustering by dynamic changes, thereby addressing the challenge of clinical and biological diversity within the ME/CFS population.

  • Jarred Younger, BA, PhD
  • Christopher Armstrong, PhD
  • Data collection complete and analysis nearly complete.
  • Paper drafting has begun but waiting for more guidance on data analysis workflow.
STUDY HYPOTHESIS AND DESCRIPTION

We’re investigating how disruptions in energy metabolism play a role in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). While past studies have found differences in certain substances in the blood of ME/CFS patients compared to healthy people, there’s no consistent marker found yet. This might be because ME/CFS patients are quite diverse in both their symptoms and biology.

To tackle this, our study uses a method called repeated-measures design. This helps reduce differences between individuals and makes our findings more reliable, especially for conditions like ME/CFS where there’s a lot of variability.

We’re collecting blood samples from ME/CFS patients every day for 25 days. By carefully analyzing these samples using this method, we hope to understand better how the body’s chemistry changes over time in ME/CFS. Our aim is to group patients based on these changing patterns rather than just their static traits, which could lead to better ways to understand and treat ME/CFS in the future.

OBJECTIVES
  1. Pattern biology that corresponds to patient symptoms over the course of a day in two international cohorts.
  2. Track the biological impact of meals, social tasks, mental tasks and exercise tasks on ME/CFS patients compared to controls.
  3. Cluster patients based on similar biology-symptom dynamics.

!function(t,e,i,n,o,c,d,s){ t.tgbWidgetOptions={id:o,domain:n}, (d=e.createElement(i)).src=[n,"widget/script.js"].join(""), d.async=1, (s=e.getElementById(c)).parentNode.insertBefore(d,s) }(window,document,"script","https://tgbwidget.com/","1189132614","tgb-widget-script");

OMF Australia accepts donations of Cryptocurrencies

Make the most of your donation by donating your Bitcoin, Ethereum, and other cryptocurrencies directly to OMF Australia rather than selling and donating the after-tax proceeds.

  • Your tax deduction will be equal to the fair market value of the donated cryptocurrency (as determined by a qualified appraisal).
  • Donors should consult with a tax advisor for properly recording this donation on a personal tax return.


OMF Australia can accept cryptocurrency donations of any amount. 

Donating cryptocurrency is a non-taxable event, meaning you do not owe capital gains tax on the appreciated amount and can deduct it on your taxes. This makes Bitcoin and other cryptocurrency donations one of the most tax-efficient ways to support your favorite cause. If you want to learn more about how donating crypto can lower your taxes, check out thegivingblock.com/faq.

Talk to a crypto-savvy tax professional or connect with The Giving Block to get connected with one.

We accept the following cryptocurrencies: Bitcoin (BTC), Ether (ETH), Litecoin (LTC), Bitcoin Cash (BCH), Zcash (ZEC), Gemini Dollar (GUSD), Basic Attention Token (BAT), Chainlink (LINK), 0x (ZRX), Storj (STORJ), Dai (DAI), Amp (AMP), The Graph (GRT), UMA (UMA), 1inch (1INCH).

ATO Crypto asset investment & tax